Maprotiline Hydrochloride

Preferred Label : Maprotiline Hydrochloride;

NCIt synonyms : 9-(gamma-Methylaminopropyl)-9,10-dihydro-9,10-ethanoanthracene Hydrochloride; 1-(3-Methylaminopropyl)dibenzo(b,e)bicyclo(2.2.2)octadiene Hydrochloride;

NCIt definition : The hydrochloride salt form of maprotiline, a tetracyclic antidepressant closely related to the tricyclic antidepressants with adrenergic activity and sedative properties. Maprotiline hydrochloride exerts its effect by blocking the re-uptake of norepinephrine, thereby increasing the synaptic concentration of norepinephrine in the central nervous system and subsequently prolonging the action of norepinephrine on central receptors.;

UNII : 7C8J54PVFI;

InChIKey : NZDMFGKECODQRY-UHFFFAOYSA-N;

CAS number : 10347-81-6;

Drug name : Ludiomil;

Chemical formula : C20H23N.HCl;

Details

Origin ID

C47594;

UMLS CUI

C0700455;

Automatic exact mappings (from CISMeF team)
- maprotiline [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- maprotiline [MeSH Descriptor]
- maprotiline [Substance BNPC]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Maprotiline [NCIt concept]
is_salt_form_of
- Maprotiline [NCIt concept]

Keyword's position in hierarchy(ies) :

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