Preferred Label : Loxapine Succinate;
NCIt synonyms : Butanedioic Acid, compound with 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine(1:1); 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz(b,f)(1,4)oxazepine Succinate(1:1); Cloxazepin;
NCIt definition : The succinate salt form of loxapine, a tricyclic dibenzoxazepine antipsychotic agent
with antiemetic, sedative, anticholinergic, and antiadrenergic actions. Loxapine succinate
exerts its actions by blocking the dopamine receptors at postsynaptic receptor sites
in the limbic system, cortical system and basal ganglia, thereby reducing the hallucinations
and delusions that are associated with schizophrenia. This agent also exerts extrapyramidal
side effects.;
UNII : X59SG0MRYU;
InChIKey : YQZBAXDVDZTKEQ-UHFFFAOYSA-N;
CAS number : 27833-64-3;
Drug name : Loxitane; Daxolin; Loxapac;
Chemical formula : C18H18ClN3O.C4H6O4;
ChEBI ID : CHEBI:6549;
Origin ID : C47590;
UMLS CUI : C0024057;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
