Loracarbef - CISMeF

Preferred Label : Loracarbef;

NCIt synonyms : (6R, 7S)-7-[(R)-2-Amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, Monohydrate;

NCIt definition : A semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic derived from cephasporium. The bactericidal activity of loracarbef results from the inhibition of bacterial cell wall synthesis through interference with the cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and causes cell lysis. Loracarbef is more active against a variety of gram-negative organisms but less active against gram-positive pathogens compared to first-generation agents.;

UNII : 3X11EVM5SU;

InChIKey : GPYKKBAAPVOCIW-HSASPSRMSA-N;

CAS number : 121961-22-6;

Drug name : Lorabid;

Chemical formula : C16H16ClN3O4.H2O;

Details

Origin ID

C47588;

UMLS CUI

C0065295;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Loracarbef [LOINC component]
- Loracarbef (substance) [SNOMED CT concept]
- Product containing loracarbef (medicinal product) [SNOMED CT concept]
- loracarbef [ATC Code]
- loracarbef [MeSH Supplementary Concept]
- loracarbef [MeSH concept]
- loracarbef [SNOMED Notion]
Validated automatic mappings to BTNT
- loracarbef [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients