" /> Levonordefrin - CISMeF





Preferred Label : Levonordefrin;

NCIt synonyms : Neo-Cobefrin; (-)-alpha-(1-Aminoethyl)-3,4-dihydroxybenzyl Alcohol; 1,2-Benzenediol, 4-(2-amino-1-hydroxypropyl)-,(R-(R*,S*))-;

NCIt definition : The levoisomer of nordefrin, a synthetic catecholamine and norepinephrine derivative with sympathomimetic and antihypertensive effects. Levonordefrin's antihypertensive effect is exerted through activation of alpha 2-adrenergic receptors in the cardiovascular control center of the CNS thereby suppressing the sympathetic output from the brain and subsequently lowering blood pressure. Levonordefrin binds to and activates peripheral alpha 2- adrenergic receptors, thereby causing vasoconstriction.;

UNII : V008L6478D;

InChIKey : GEFQWZLICWMTKF-CDUCUWFYSA-N;

CAS number : 829-74-3; 18829-78-2;

Chemical formula : C9H13NO3;

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30/05/2025


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