Preferred Label : Levomethadyl Acetate Hydrochloride;
NCIt synonyms : l-Acetylmethadol Hydrochloride; 3-Heptanol, 6-(dimethylamino)-4,4-diphenyl-, Acetate (Ester), (3S,6S)-(-)-; Benzeneethanol, beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, Acetate(Ester);
NCIt definition : The hydrochloride salt form of levomethadyl acetate, a synthetic mu-receptor agonist
with analgesic activity. Levomethadyl acetate hydrochloride mimics the actions of
endogenous peptides at CNS opioid receptors, including analgesia, euphoria, sedation,
respiratory depression, miosis, bradycardia and physical dependence. Levomethadyl
acetate hydrochloride has less severe withdrawal symptoms compared to the morphine-like
agents. In addition, with chronic use, levomethadyl acetate hydrochloride produces
cross-tolerance to the effects of other mu-receptor agonists, thereby decreasing the
physical dependence.;
UNII : B54CW5KG52;
InChIKey : UXBPQRGCVJOTNT-COBSGTNCSA-N;
CAS number : 43033-72-3; 38821-43-1;
Drug name : Orlaam;
Chemical formula : C23H31NO2.HCl;
Origin ID : C47583;
UMLS CUI : C0282232;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
