Ketotifen Fumarate

Preferred Label : Ketotifen Fumarate;

NCIt synonyms : 4-(1-Methyl-4-piperidylidene)-4H-benzo[4,5]cyclohepta[1,2-b] thiophen-10(9H)-one hydrogen fumarate; 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-,(E)-2-butenedioate(1:1);

NCIt definition : The fumarate salt of ketotifen, a cycloheptathiophene derivative with anti-allergic activity. Ketotifen selectively blocks histamine (H1) receptors and prevents the typical symptoms caused by histamine release. This agent also interferes with the release of inflammatory mediators from mast cells involved in hypersensitivity reactions, thereby decreasing chemotaxis and activation of eosinophils.;

UNII : HBD503WORO;

InChIKey : YNQQEYBLVYAWNX-WLHGVMLRSA-N;

CAS number : 34580-14-8;

Drug name : Zaditen; Zaditor;

Chemical formula : C19H19NOS.C4H4O4;

Details

Origin ID

C47579;

UMLS CUI

C0043443;

Automatic exact mappings (from CISMeF team)
- ketotifen [Substance BNPC]
- ketotifen [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
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- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
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- Ketotifen [NCIt concept]
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- Ketotifen [NCIt concept]

Keyword's position in hierarchy(ies) :

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