NCIt definition : A pyrazole with competitive alcohol dehydrogenase inhibitor activity. Fomepizole prevents
the metabolism of ethylene glycol and methanol by alcohol dehydrogenase, thereby inhibiting
the formation of their toxic metabolites, glycolate and oxalate (from ethylene glycol),
and formic acid (from methanol). Fomepizole is indicated for use as an antidote in
ethylene glycol and methanol poisoning. (NCI05);