NCIt definition : The diacetate salt form of ethynodiol, a semi-synthetic progestational hormone agonist.
Ethynodiol diacetate binds to cytoplasmic progesterone receptors in the reproductive
system and subsequently activates progesterone receptor mediated gene expression.
As a result of the negative feedback mechanism, luteinizing hormone (LH) release is
inhibited, which leads to an inhibition of ovulation and an alteration in the cervical
mucus and endometrium. In addition, ethynodiol diacetate has weak oestrogenic and
androgenic properties.;