Ethotoin - CISMeF

Preferred Label : Ethotoin;

NCIt synonyms : Hydantoin, 3-ethyl-5-phenyl-; 3-ethyl-5-phenyl-2,4-imidazolidinedione;

NCIt definition : A hydantoin anticonvulsant with anti-epileptic activity. The mechanism of action is not completely known, but is thought to be fairly similar to phenytoin. Ethotoin influences synaptic transmission by altering sodium and calcium ion influx across neuronal membranes in the repolarization, depolarization, and membrane stability phase and interferes with the calcium uptake in presynaptic terminals. This inhibits neuronal firing and results in the stabilization of neuronal membranes, thereby preventing the spread of seizure activity at the motor cortex.;

UNII : 46QG38NC4U;

InChIKey : SZQIFWWUIBRPBZ-UHFFFAOYSA-N;

CAS number : 86-35-1;

Drug name : Peganone;

Chemical formula : C11H12N2O2;

ChEBI ID : CHEBI:4888;

Details

Origin ID

C47524;

UMLS CUI

C0015046;

Automatic exact mappings (from CISMeF team)
- Ethotoin [ICHI extension code]
Currated CISMeF NLP mapping
- Ethotoin [ICD-11 Extension code]
- Ethotoin [LOINC component]
- Ethotoin (substance) [SNOMED CT concept]
- ethotoin [Substance BNPC]
- ethotoin [MeSH concept]
- ethotoin [MeSH Supplementary Concept]
- ethotoin [SNOMED Notion]
See also inter- (CISMeF)
- Product containing ethotoin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ethotoin [ICD-11 Extension code]
- Ethotoin [LOINC component]
- Ethotoin (substance) [SNOMED CT concept]
- Product containing ethotoin (medicinal product) [SNOMED CT concept]
- ethotoin [ATC Code]
- ethotoin [Substance BNPC]
- ethotoin [MeSH Supplementary Concept]
- ethotoin [MeSH concept]
- ethotoin [SNOMED Notion]
Validated automatic mappings to BTNT
- ethotoin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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