Ethosuximide - CISMeF

Preferred Label : Ethosuximide;

NCIt synonyms : 3-Ethyl-3-methylpyrrolidine-2,5-dione;

NCIt definition : A succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures.;

UNII : 5SEH9X1D1D;

InChIKey : HAPOVYFOVVWLRS-UHFFFAOYSA-N;

CAS number : 77-67-8;

Drug name : Zarontin;

Chemical formula : C7H11NO2;

NSC code : 64013;

ChEBI ID : CHEBI:4887;

Details

Origin ID

C47523;

UMLS CUI

C0015043;

Automatic exact mappings (from CISMeF team)
- ethosuximide [medical devices type]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ethosuximide [ICD-11 Extension code]
- Ethosuximide [LOINC component]
- Ethosuximide (substance) [SNOMED CT concept]
- Product containing ethosuximide (medicinal product) [SNOMED CT concept]
- ethosuximide [ATC Code]
- ethosuximide [Substance BNPC]
- ethosuximide [MeSH concept]
- ethosuximide [MeSH Descriptor]
- ethosuximide [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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