" /> Esmolol Hydrochloride - CISMeF





Preferred Label : Esmolol Hydrochloride;

NCIt synonyms : ( -)-Methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate Hydrochloride; 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoic Acid Methyl Ester HCl;

NCIt definition : The hydrochloride salt form of esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation.;

UNII : V05260LC8D;

InChIKey : GEKNCWBANDDJJL-UHFFFAOYSA-N;

CAS number : 81161-17-3;

Drug name : Brevibloc;

Molecule name : ASL 8052;

Chemical formula : C16H25NO4.HCl;

ChEBI ID : CHEBI:4857;

Codes from synonyms : 32067;

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08/05/2025


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