NCIt definition : The mesylate salt form of eprosartan, a non-biphenyl, non-tetrazole, nonpeptide angiotensin
II antagonist with antihypertensive activity. Eprosartan mesylate antagonizes angiotensin
II type I receptors in tissues such as vascular smooth muscle and the adrenal gland.
This prevents angiotensin II-induced vasoconstriction and prevents angiotensin II-mediated
stimulation of aldosterone secretion by the adrenal cortex, which decreases the excretion
of sodium and water and increases the excretion of potassium.;