Eplerenone - CISMeF

Preferred Label : Eplerenone;

NCIt synonyms : 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester;

NCIt definition : A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerenone is used in the treatment of hypertension and congestive heart failure.;

UNII : 6995V82D0B;

InChIKey : JUKPWJGBANNWMW-VWBFHTRKSA-N;

CAS number : 107724-20-9;

Drug name : Inspra;

Chemical formula : C24H30O6;

ChEBI ID : CHEBI:31547;

Codes from synonyms : 20109;

Details

Origin ID

C47513;

UMLS CUI

C0961485;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Eplerenone [MeSH Descriptor]
- Eplerenone (substance) [SNOMED CT concept]
- Product containing eplerenone (medicinal product) [SNOMED CT concept]
- eplerenone [ATC Code]
- eplerenone [MeSH concept]
Validated automatic mappings to BTNT
- eplerenone [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients