Pigmented Spindle Cell Nevus

Preferred Label : Pigmented Spindle Cell Nevus;

NCIt synonyms : Spindle Cell Nevus of Reed; Reed Nevus; PSCN; Pigmented Spindle Cell Variant of Spitz Nevus; Pigmented Spindle Cell Spitz Nevus;

NCIt related terms : Pigmented spindle cell nevus of Reed;

NCIt definition : A subtype of Spitz nevus characterized by the presence of heavily pigmented spindle-shaped melanocytes that proliferate in the epidermis or in the epidermis and superficial dermis. It presents as a small and slightly elevated brown or black skin lesion with usually well-demarcated borders. Sometimes the clinical and morphologic features may be difficult to distinguish from melanoma.;

Neoplastic status : Benign;

Details

Origin ID

C4751;

UMLS CUI

C0474967;

Currated CISMeF NLP mapping
- Pigmented spindle cell naevus of Reed [ICD-11 Extension code]
- Spindle cell nevus of Reed (disorder) [SNOMED CT concept]
Disease excludes abnormal cell
- Malignant Cell [NCIt concept]
- Melanoma Cell [NCIt concept]
Disease may have findings
- Dermal Involvement [NCIt concept]
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- MAPK Pathway Activated [NCIt concept]
- NTRK3 Fusion Positive [NCIt concept]
- Papular Lesion [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
- Skin Plaque [NCIt concept]
Excludes anatomical site(s)
- Conjunctiva [NCIt concept]
Has associated anatomic sites
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
See also inter- (CISMeF)
- Epithelioid and spindle cell nevus (morphologic abnormality) [SNOMED CT concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Spindle cell nevus of Reed (disorder) [SNOMED CT concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
disease_excludes_finding
- Atypia [NCIt concept]
- Dysplasia [NCIt concept]
- Invasive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_excludes_molecular_abnormality
- BRAF Gene Mutation [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Melanocyte [NCIt concept]
- Nevus Cell [NCIt concept]
- Spindle Melanocyte [NCIt concept]
disease_has_finding
- Benign Cellular Infiltrate [NCIt concept]
- Cutaneous Involvement [NCIt concept]
- Junctional Proliferation [NCIt concept]
- Melanin Pigment Present [NCIt concept]
disease_has_normal_cell_origin
- Melanocyte [NCIt concept]
disease_has_normal_tissue_origin
- Skin Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Skin [NCIt concept]
disease_may_have_molecular_abnormality
- Activating HRAS Mutation [NCIt concept]

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