" /> Emtricitabine - CISMeF





Preferred Label : Emtricitabine;

NCIt synonyms : FTC; 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-,(2R-cis)-; (-)-2'-Deoxy-5-fluoro-3'-thiacytidine; dOTFC;

NCIt definition : A synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate within the cell. This metabolite inhibits the activity of human immunodeficiency virus (HIV) reverse transcriptase both by competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack of the essential 3'-OH group).;

UNII : G70B4ETF4S;

InChIKey : XQSPYNMVSIKCOC-NTSWFWBYSA-N;

CAS number : 143491-57-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 143491-57-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Emtriva; Coviracil;

Molecule name : BW-524W91;

Chemical formula : C8H10FN3O3S;

ChEBI ID : CHEBI:31536;

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22/05/2024


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