NCIt definition : A triptan with specific affinity for the 5-hydroxytriptamine1B/1D receptor. Eletriptan
hydrobromide binds to and acts at serotonin 5-HT1B receptors located on intracranial
blood vessels which leads to vasoconstriction. This drug may also exerts its effects
by binding to and activating 5-HT 1D receptors on sensory nerve endings in the trigeminal
system, which results in the inhibition of pro-inflammatory neuropeptide release.
Eletriptan hydrobromide is used to relieve pain or symptoms associated with migraine
headaches.;