" /> Echothiophate Iodide - CISMeF





Preferred Label : Echothiophate Iodide;

NCIt synonyms : (2-Mercaptoethyl)trimethylammonium Iodide S-ester with O,O-diethyl Phosphorothioate, Diethoxyphosphoryl-thiocholine Iodide; 2-((Diethoxyphosphinyl)thio)-N,N,N,-trimethylethanaminium Iodide;

NCIt definition : The iodide salt form of echothiophate, a long-acting cholinesterase inhibitor with parasympathomimetic activity. Echothiophate iodide potentiates the action of endogenous acetylcholine by inhibiting acetylcholinesterase that hydrolyzes acetylcholine. When applied topically to the eye, this agent prolongs stimulation of the parasympathetic receptors at the neuromuscular junctions of the longitudinal muscle of the ciliary body. Contraction of longitudinal muscle pulls on the scleral spur, and opens the trabecular meshwork, thereby increases aqueous humor outflow from the eye and reduces intraocular pressure.;

UNII : BA9QH3P00T;

InChIKey : OVXQHPWHMXOFRD-UHFFFAOYSA-M;

CAS number : 513-10-0;

Drug name : Phospholine Iodide;

Chemical formula : C9H23NO3PS.I;

ChEBI ID : CHEBI:59849;

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19/07/2025


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