Drospirenone - CISMeF

Preferred Label : Drospirenone;

NCIt synonyms : 1,2-Dihydrospirorenone; 6-beta,7-beta:15-beta,16-beta-Dimethylene-3-oxo-17-alpha-pregn-4-ene-21,17-carbolactone; (6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-1,3',4',6,6a,7,8,9,10,11,12,13,14,15,15a,16-Hexadecahydro-10,13-dimethylspiro-(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione;

NCIt definition : A synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity. Drospirenone binds to the progesterone receptor, the resulting complex becomes activated and binds to specific sites on DNA. This results in a suppression of LH activity and an inhibition of ovulation as well as an alteration in the cervical mucus and endometrium. This leads to an increased difficulty of sperm entry into the uterus and implantation. This drug is used in oral contraceptives.;

UNII : N295J34A25;

InChIKey : METQSPRSQINEEU-HXCATZOESA-N;

CAS number : 67392-87-4;

Chemical formula : C24H30O3;

ChEBI ID : CHEBI:50838;

Details

Origin ID

C47502;

UMLS CUI

C0043822;

See also inter- (CISMeF)
- Product containing drospirenone (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Drospirenone (substance) [SNOMED CT concept]
- Product containing drospirenone (medicinal product) [SNOMED CT concept]
- drospirenone [ATC Code]
- drospirenone [Substance BNPC]
- drospirenone [MeSH concept]
- drospirenone [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- drospirenone [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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