Dirithromycin - CISMeF

Preferred Label : Dirithromycin;

NCIt synonyms : Erythromycin, 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethylidene)oxy)-,(9S(R))-;

NCIt definition : A semi-synthetic macrolide antibiotic pro-drug. Dirithromycin is converted by hydrolysis during intestinal absorption into the microbiologically active erythromycylamine. Eryhtromylamine binds to the 50 S subunit of the 70 S ribosome of susceptible organisms, thereby inhibiting bacterial RNA-dependent protein synthesis. This antibiotic is used in the treatment of infections of the respiratory tract, skin and soft tissue caused by gram-positive microorganisms, including S. aureus, S. pneumonia and pyogenes, gram-negative microorganisms, including H. influenzae, L. pneumophila, M. catarrhalis, and M. pneumoniae.;

UNII : 1801D76STL;

InChIKey : WLOHNSSYAXHWNR-DWIOZXRMSA-N;

CAS number : 62013-04-1;

Drug name : Dynabac;

Chemical formula : C42H78N2O14;

ChEBI ID : CHEBI:474014;

Details

Origin ID

C47496;

UMLS CUI

C0058445;

Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Dirithromycin [LOINC component]
- Dirithromycin (substance) [SNOMED CT concept]
- Product containing dirithromycin (medicinal product) [SNOMED CT concept]
- dirithromycin [ATC Code]
- dirithromycin [SNOMED Notion]
- dirithromycin [MeSH concept]
- dirithromycin [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- dirithromycin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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