Dimercaprol - CISMeF

Preferred Label : Dimercaprol;

NCIt synonyms : 1,2-Dithioglycerol; 2,3-Dimercapto-1-propanol;

NCIt definition : A metal chelating agent that is used as an antidote in arsenic, gold, lead, mercury and other heavy metal poisoning. Metals form ligands in the body with the sulfhydryl groups of the pyruvate-oxidase enzyme system. This leads to an inhibition of the normal functioning of these enzymes that are dependent on free sulfhydryl groups for their activity. Dimercaprol reverses the enzyme inhibition by chelating the metal and regenerates free sulfhydryl groups, thereby preventing and reversing the metals toxic effects.;

UNII : 0CPP32S55X;

InChIKey : WQABCVAJNWAXTE-UHFFFAOYSA-N;

CAS number : 59-52-9;

Drug name : BAL in Oil;

Chemical formula : C3H8OS2;

NSC code : 39515;

ChEBI ID : CHEBI:64198;

Codes from synonyms : 30435;

Details

Origin ID

C47494;

UMLS CUI

C0012383;

False automatic mappings
- 1,3-dimercapto-2-propanol [MeSH concept]
- 1,3-dimercapto-2-propanol [MeSH Supplementary Concept]
- 1,3-dimercaptopropan-2-ol [Substance BNPC]
- Bronchoalveolar lavage [LOINC System]
See also inter- (CISMeF)
- Product containing dimercaprol (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Bronchoalveolar lavage [LOINC System]
- Dimercaprol [ICD-11 Extension code]
- Dimercaprol (substance) [SNOMED CT concept]
- Product containing dimercaprol (medicinal product) [SNOMED CT concept]
- dimercaprol [ATC Code]
- dimercaprol [Substance BNPC]
- dimercaprol [SNOMED Notion]
- dimercaprol [MeSH concept]
- dimercaprol [MeSH Descriptor]
Validated automatic mappings to BTNT
- dimercaprol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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