Preferred Label : Dihydroergotamine Mesylate;
NCIt synonyms : 9,10-Dihydroergotamine Mesylate; Ergotoman-3',6',18-trione,9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-,(5'alpha)-,
monomethanesulfonate(salt);
NCIt definition : An ergot derivative with agonistic activity for alpha-adrenergic, serotonergic, and
dopaminergic receptors. Dihydroergotamine mesylate most likely relieves migraine headaches
by binding to and stimulating the 5-HT1D receptor subtype, thereby causing constriction
of cerebral blood vessels. However, it has also been proposed that dihydroergotamine
mesylate acts upon 5-HT1D receptors on sensory nerve endings of the trigeminal system,
thereby decreasing the release of pro-inflammatory neuropeptide release.;
UNII : 81AXN7R2QT;
InChIKey : ADYPXRFPBQGGAH-UMYZUSPBSA-N;
CAS number : 6190-39-2;
Drug name : Migranal;
Chemical formula : C33H37N5O5.CH4O3S;
ChEBI ID : CHEBI:59756;
Origin ID : C47491;
UMLS CUI : C0700532;
See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
