NCIt definition : A synthetic sympathomimetic amine with CNS stimulating properties. Dexmethylphenidate
hydrochloride acts by facilitating the release of catecholamines, particularly noradrenaline
and dopamine, from nerve terminals in the brain and inhibits their uptake. This leads
to an increase in motor activity, causes euphoria, mental alertness and excitement
and suppresses appetite. This drug causes dependence and may cause an increase in
heart rate and blood pressure. It is used in the treatment of attention deficit hyperactivity
disorder. It may also be used in the treatment of fatigue and other nervous system
effects seen with chemotherapy.;