NCIt definition : A semi-synthetic beta-lactam aminocyclohexylpenicillin antibiotic. Cyclacillin is
bactericidal and binds to specific penicillin-binding proteins, thereby inhibiting
transpeptidation during peptidoglycan synthesis. This leads to an interruption of
the bacterial cell wall, causing instability of bacterial cell wall and results in
cell lysis. Cyclacillin is beta-lactamase susceptible.;