Preferred Label : Clorazepate Dipotassium;
NCIt synonyms : Potassium 7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylate
KOH; 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, Monopotassium
Salt, compound with Potassium Hydroxide;
NCIt definition : A benzodiazepine with anxiolytic, sedative, hypnotic, and anticonvulsant properties.
Clorazepate dipotassium exerts its effect by de-activating the nervous system through
potentiation of the inhibitory effect of gamma-aminobutyric acid (GABA) on the GABA-A
receptors by binding to a site that is distinct from the GABA binding site. Its inhibitory
effect is caused by an increase in GABA-mediated chloride channel opening events,
leading to hyperpolarization and synaptic inhibition.;
UNII : 63FN7G03XY;
InChIKey : QCHSEDTUUKDTIG-UHFFFAOYSA-L;
CAS number : 57109-90-7; 15585-90-7;
Drug name : Tranxene; Gen-Xene;
Chemical formula : C16H10ClN2O3.2K.HO;
ChEBI ID : CHEBI:3762;
Origin ID : C47459;
UMLS CUI : C0009033;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
