Clofazimine - CISMeF

Preferred Label : Clofazimine;

NCIt synonyms : 3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine; 2-Phenazinamine, 3,5-dihydro-N,5-bis(4-chlorophenyl)-3-((1-methylethyl)imino)-;

NCIt definition : A phenazine dye with anti-mycobacterial and anti-inflammatory activities. The exact mechanism through which clofazimine exerts its effect is unknown. However, it binds preferentially to mycobacterial DNA, thereby inhibiting DNA replication and cell growth. Clofazimine has a slow bactericidal effect on Mycobacterium leprae and is active against various other Mycobacteria.;

UNII : D959AE5USF;

InChIKey : WDQPAMHFFCXSNU-BGABXYSRSA-N;

CAS number : 2030-63-9;

Drug name : Lamprene;

NSC code : 141046;

ChEBI ID : CHEBI:3749;

Details

Origin ID

C47456;

UMLS CUI

C0008996;

See also inter- (CISMeF)
- Product containing clofazimine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Clofazimine [ICD-11 Extension code]
- Clofazimine [LOINC component]
- Clofazimine (substance) [SNOMED CT concept]
- Product containing clofazimine (medicinal product) [SNOMED CT concept]
- clofazimine [ATC Code]
- clofazimine [Substance BNPC]
- clofazimine [MeSH Descriptor]
- clofazimine [MeSH concept]
- clofazimine [SNOMED Notion]
Validated automatic mappings to BTNT
- clofazimine [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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