Chloroprocaine Hydrochloride

Preferred Label : Chloroprocaine Hydrochloride;

NCIt synonyms : Nesacaine; Benzoic Acid, 4-amino-2-chloro-, 2-(diethylamino)ethyl Ester, Hydrochloride; 2-Diethylaminoethyl 4-amino-2-chlorobenzoate Hydrochloride;

NCIt related terms : Chloroprocaine;

NCIt definition : A synthetic, aminoester, local, anesthetic agent. At the injection site, chloroprocaine hydrochloride acts by inhibiting sodium influx through binding to specific membrane sodium ion channels in the neuronal cell membranes, restricting sodium permeability, and blocking nerve impulse conduction. This leads to a loss of sensation. Chloroprocaine hydrochloride is short-acting due to rapid hydrolysis by pseudocholinesterase into para-aminobenzoic acid in plasma.;

UNII : LT7Z1YW11H;

InChIKey : SZKQYDBPUCZLRX-UHFFFAOYSA-N;

CAS number : 3858-89-7;

Chemical formula : C13H19ClN2O2.HCl;

ChEBI ID : CHEBI:3637;

Details

Origin ID

C47444;

UMLS CUI

C0132182;

Automatic exact mappings (from CISMeF team)
- Nesacaine [ICHI extension code]
- Nesacaine [ICD-11 Extension code]
- chloroprocaine [ATC Code]
- nesacaine [MeSH concept]
Currated CISMeF NLP mapping
- 2-DIETHYLAMINOETHYL 4-AMINO-2-CHLOROBENZOATE HYDROCHLORIDE [Substance BNPC]
- Chloroprocaine hydrochloride [SMS substance]
- Chloroprocaine hydrochloride (substance) [SNOMED CT concept]
- chloroprocaine hydrochloride [International Nonproprietary Name]
- chloroprocaine hydrochloride [MeSH concept]
- chloroprocaine hydrochloride [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 2-DIETHYLAMINOETHYL 4-AMINO-2-CHLOROBENZOATE HYDROCHLORIDE [Substance BNPC]
- Chloroprocaine hydrochloride (substance) [SNOMED CT concept]
- Nesacaine [ICD-11 Extension code]
- chloroprocaine hydrochloride [International Nonproprietary Name]
- chloroprocaine hydrochloride [SNOMED Notion]
- chloroprocaine hydrochloride [MeSH concept]
Validated automatic mappings to NTBT
- Chloroprocaine [ICD-11 Extension code]
- Chloroprocaine [ICHI extension code]
- Chloroprocaine [SMS substance]
- Chloroprocaine (substance) [SNOMED CT concept]
- chloroprocaine [SNOMED Notion]
- chloroprocaine [MeSH concept]
- chloroprocaine [MeSH Supplementary Concept]
concept_is_in_subset
- CPTAC Baseline Medical Forms Terminology [NCIt concept]
- CPTAC Surgery-Anesthesia Form [NCIt concept]
- CPTAC Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Chloroprocaine [NCIt concept]
is_salt_form_of
- Chloroprocaine [NCIt concept]

Keyword's position in hierarchy(ies) :

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