NCIt definition : The sodium salt form of ceftizoxime and a semi-synthetic, broad-spectrum, beta-lactamase
resistant, third-generation cephalosporin antibiotic with bactericidal activity. Ceftizoxime
sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins
(PBPs) thereby interfering with the final transpeptidation step required for cross-linking
of peptidoglycan units which are a component of the cell wall. Lack of cross-linking
results in a reduction of cell wall stability and leads to cell lysis.;