Carbidopa - CISMeF

Preferred Label : Carbidopa;

NCIt synonyms : alpha-Methyldopahydrazine; (-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic Acid; Benzenepropanoic Acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-,(S)-;

NCIt definition : A hydrazine derivative of dopa. Carbidopa is a peripheral dopa decarboxylase inhibitor that is used as an adjunct to levodopa administration to prevent peripheral biosynthesis of levodopa to dopamine, thereby reducing peripheral side effects. Carbidopa does not penetrate the blood brain barrier so that levodopa, after it reaches the brain, can be metabolized to dopamine by dopa decarboxylase where it exerts its effect on dopamine receptors.;

UNII : MNX7R8C5VO;

InChIKey : QTAOMKOIBXZKND-PPHPATTJSA-N;

CAS number : 38821-49-7;

Drug name : Lodosyn;

Chemical formula : C10H14N2O4.H2O;

ChEBI ID : CHEBI:3395;

Details

Origin ID

C47431;

UMLS CUI

C0006982;

Automatic exact mappings (from CISMeF team)
- Levodopa with carbidopa [ICD-11 Extension code]
- Product containing carbidopa (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Carbidopa [LOINC component]
- Carbidopa (substance) [SNOMED CT concept]
- Product containing carbidopa (medicinal product) [SNOMED CT concept]
- carbidopa [Substance BNPC]
- carbidopa [SNOMED Notion]
- carbidopa [MeSH concept]
- carbidopa [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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