Preferred Label : Butalbital;
NCIt synonyms : Allylbarbital; Optalidon; Allylbarbituric Acid; 5-Allyl-5-isobutylbarbituric Acid; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(2-Methylpropyl)-5-(2-propenyl)-;
NCIt definition : A barbiturate that exerts its effect by mimicking the inhibitory effect of gamma-aminobutyric
acid (GABA) by binding to a site, distinct from the benzodiazepine binding site, on
the GABA receptor. This leads to an increase in the duration of GABA-mediated opening
of chloride channels and enhances the inhibitory effect of GABA. Consequently, its
physiologic effects include sedation, hypnosis, reduction of anxiety, and respiratory
depression and the drug causes tolerance and dependence.;
UNII : KHS0AZ4JVK;
InChIKey : UZVHFVZFNXBMQJ-UHFFFAOYSA-N;
CAS number : 77-26-9;
Chemical formula : C11H16N2O3;
ChEBI ID : CHEBI:102524;
Origin ID : C47425;
UMLS CUI : C0054234;
Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
