Azelaic Acid - CISMeF

Preferred Label : Azelaic Acid;

NCIt synonyms : Heptanedicarboxylic Acid; Lepargylic Acid; 1,9-Nonanedioic Acid;

NCIt definition : A naturally occurring dicarboxylic acid produced by Malassezia furfur and found in whole grain cereals, rye, barley and animal products. Azelaic acid possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity. Azelaic acid is bactericidal against Proprionibacterium acnes and Staphylococcus epidermidis due to its inhibitory effect on the synthesis of microbial cellular proteins. Azelaic acid exerts its keratolytic and comedolytic effects by reducing the thickness of the stratum corneum and decreasing the number of keratohyalin granules by reducing the amount and distribution of filaggrin in epidermal layers. Azelaic acid also possesses a direct anti-inflammatory effect due to its scavenger activity of free oxygen radical. This drug is used topically to reduce inflammation associated with acne and rosacea.;

UNII : F2VW3D43YT;

InChIKey : BDJRBEYXGGNYIS-UHFFFAOYSA-N;

CAS number : 123-99-9;

Drug name : Finacea; Azelex;

Molecule name : ZK 62498;

Chemical formula : C9H16O4;

NSC code : 19493;

ChEBI ID : CHEBI:48131;

Details

Origin ID

C47407;

UMLS CUI

C0052761;

See also inter- (CISMeF)
- Product containing azelaic acid (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Azelaic acid [ICD-11 Extension code]
- Azelaic acid (substance) [SNOMED CT concept]
- Product containing azelaic acid (medicinal product) [SNOMED CT concept]
- azelaic acid [ATC Code]
- azelaic acid [Substance BNPC]
- azelaic acid [MeSH concept]
- azelaic acid [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients