NCIt definition : A quinoline derivate and atypical anti-psychotic agent. Aripiprazole has partial agonistic
activity at dopamine D2 receptors and serotonin 5-HT1A receptors, as well as potent
antagonistic activity on serotonin 5-HT2A receptors. This drug stabilizes dopamine
and serotonin activity in the limbic and cortical system. Aripiprazole is used in
managing symptoms of schizophrenia and of acute manic and mixed episodes associated
with bipolar I disorders.;