Preferred Label : Antazoline Phosphate;
NCIt synonyms : 2-((N-Benzylanilino)methyl)-2-imidazoline Phosphate(1:1); N-Benzyl-4,5-dihydro-N-phenyl-1H-imidazole-2-methylamine Monophosphate; 1H-Imidazole-2-methanamine, 4,5-Dihydro-N-phenyl-N-(phenylmethyl)-, Phosphate(1:1);
NCIt definition : The phosphate salt of antazoline, an ethylenediamine derivative with histamine H1
antagonistic and sedative properties. Antazoline antagonizes histamine H1 receptor
and prevents the typical allergic symptoms caused by histamine activities on capillaries,
skin, mucous membranes, gastrointestinal and bronchial smooth muscles. These histamine
activities include vasodilation, bronchoconstriction, increased vascular permeability,
pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Antazoline
is used to provide symptomatic relieve of allergic symptoms.;
UNII : VPR5FPH326;
InChIKey : DUIGUKRYYAGJAF-UHFFFAOYSA-N;
CAS number : 154-68-7;
Chemical formula : C17H19N3.H3O4P;
Origin ID : C47399;
UMLS CUI : C0003144;
Currated CISMeF NLP mapping
- False automatic mappings
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
