NCIt definition : An anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory
mediators, including leukotrienes and histamine, from mast cells, neutrophils, and
mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase
inhibitor. Amlexanox decreases the time ulcers take to heal as well as the pain associated
with the ulcers.;