Preferred Label : Alosetron Hydrochloride;
NCIt synonyms : 1H-Pyrido(4,3-b)indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2((5-methyl-1H-imidazol-4-yl)methyl)-,
Monohydrochloride; 2,3,4,5-Tetrahydro-5-methyl-2-((5-methylimidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one
Monohydrochloride;
NCIt definition : The hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.
Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous
system, particularly on enteric and nociceptive sensory neurons, thereby affecting
the regulation of visceral pain, decreasing gastrointestinal contraction and motility,
and decreasing gastrointestinal secretions. This agent is used to treat diarrhea-predominant
irritable bowel syndrome in women.;
UNII : 2F5R1A46YW;
InChIKey : FNYQZOVOVDSGJH-UHFFFAOYSA-N;
CAS number : 122852-69-1;
Drug name : Lotronex;
Molecule name : GR 68755c;
Chemical formula : C17H18N4O.ClH;
ChEBI ID : CHEBI:53783;
Origin ID : C47386;
UMLS CUI : C0291771;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
- has_free_acid_or_base_form
- is_salt_form_of
