Preferred Label : Acrivastine;
NCIt synonyms : (E)-6-((E)-3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)-2-pyridineacrylic Acid; 2-Propenoic Acid, 3-(6-(1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-2-pyridinyl)-,(E,E)-;
NCIt definition : A synthetic alkylamine with non-sedative antihistaminergic activity. Acrivastine competitively
blocks the histamine H1 receptor and limits the typical allergic and anaphylactic
responses, including bronchoconstriction, vasodilation, increased capillary permeability,
and spasmodic contraction of gastrointestinal smooth muscle, caused by actions of
histamine on bronchial, and gastrointestinal smooth muscles, and on capillaries. This
drug also prevents histamine-induced pain and itching of the skin and mucous membranes.
(NCI05);
UNII : A20F9XAI7W;
InChIKey : PWACSDKDOHSSQD-IUTFFREVSA-N;
CAS number : 87848-99-5;
Drug name : Semprex;
Molecule name : BW 825C;
Chemical formula : C22H24N2O2;
Origin ID : C47383;
UMLS CUI : C0054340;
Currated CISMeF NLP mapping
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
