Giant Cell Fibroblastoma

Preferred Label : Giant Cell Fibroblastoma;

NCIt synonyms : GCF; Dermatofibrosarcoma Protuberans with Giant Cell Fibroblastoma-Like Differentiation;

NCIt definition : A morphologic variant of dermatofibrosarcoma protuberans that is most often seen in childhood and is characterized by the presence of spindle-shaped fibroblastic cells, a storiform growth pattern, numerous multinucleated giant cells, wide vessel-like spaces, and extensive myxoid change.;

Alternative definition : NCI-GLOSS: A rare type of soft tissue tumor marked by painless nodules in the dermis (the inner layer of the two main layers of tissue that make up the skin) and subcutaneous (beneath the skin) tissue. These tumors may come back after surgery, but they do not spread to other parts of the body. They occur mostly in boys and are related to dermatofibrosarcoma protuberans.;

Neoplastic status : Undetermined;

ICD-O code : 8834/1;

Codes from synonyms : CDR0000390282;

Details

Origin ID

C4700;

UMLS CUI

C3693482;

Automatic exact mappings (from CISMeF team)
- Giant Cell Fibroblastoma [MeSH concept]
- Giant cell fibroblastoma [ICD-O code]
- Giant cell fibroblastoma [ICD-11 Extension code]
Disease excludes normal cell origin
- Epithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Excludes anatomical site(s)
- Bone [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
Manual NTBT mappings (CISMeF)
- fibroblastoma [Disease (Nov.)]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Dermatofibrosarcoma protuberans [OMIM Phenotype]
- Giant Cell Fibroblastoma [MeSH concept]
- Giant cell fibroblastoma (morphologic abnormality) [SNOMED CT concept]
- Giant cell fibroblastoma of skin (disorder) [SNOMED CT concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Well-Circumscribed Lesion [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_abnormal_cell
- Giant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Fibroblast [NCIt concept]
- Neoplastic Spindle-Shaped Fibroblast [NCIt concept]
disease_has_finding
- Cutaneous Involvement [NCIt concept]
- Invasive Lesion [NCIt concept]
- Locally Aggressive Lesion [NCIt concept]
- Multinodular Mass [NCIt concept]
- Storiform Growth Pattern [NCIt concept]
- Wide Vessel-Like Spaces Formation [NCIt concept]
disease_has_normal_cell_origin
- Connective and Soft Tissue Cell [NCIt concept]
- Fibroblast [NCIt concept]
disease_has_normal_tissue_origin
- Connective and Soft Tissue [NCIt concept]
- Soft Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Dermis [NCIt concept]
- Skin [NCIt concept]
disease_mapped_to_gene
- COL1A1/PDGFB Fusion Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Supernumerary Circular Chromosome [NCIt concept]
- t(17;22)(q22;q13) [NCIt concept]
disease_may_have_molecular_abnormality
- COL1A1-PDGFbeta Fusion Protein Expression [NCIt concept]
pathogenesis_of_disease_involves_gene
- COL1A1/PDGFB Fusion Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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