Gestational Choriocarcinoma

Preferred Label : Gestational Choriocarcinoma;

NCIt definition : A rare, highly malignant epithelial tumor that develops from a hydatidiform mole (50%), following abortion (25%), or during normal pregnancy (22%). It is characterized by the presence of invasive and anaplastic trophoblastic tissue composed of intermediate trophoblastic cells, cytotrophoblasts and syncytiotrophoblasts, abundant vascularity, and secretion of human chorionic gonadotropin. Because of rapid growth and a high propensity for hemorrhage, this neoplasm often constitutes a medical emergency.;

Neoplastic status : Malignant;

Details

Origin ID

C4646;

UMLS CUI

C0349557;

Automatic exact mappings (from CISMeF team)
- Gestational choriocarcinoma [ICD-11 More detail]
- Gestational choriocarcinoma (morphologic abnormality) [SNOMED CT concept]
- choriocarcinoma, non-gestational [MeSH Descriptor]
Currated CISMeF NLP mapping
- Choriocarcinoma [MedDRA Preferred Term]
- Gestational choriocarcinoma [ORDO Disease]
- Gestational choriocarcinoma (disorder) [SNOMED CT concept]
- choriocarcinoma [MeSH Descriptor]
- choriocarcinoma [MeSH concept]
- choriocarcinoma, nos [SNOMED Notion]
- gestational choriocarcinoma [DO Concept]
- gestational choriocarcinoma [Disease (Nov.)]
DO Cross reference
- gestational choriocarcinoma [DO Concept]
Disease excludes abnormal cell
- Malignant Round Germ Cell with Glycogen-Rich Cytoplasm and Round Nucleus [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Hemorrhage [NCIt concept]
- Necrotic Change [NCIt concept]
Has associated anatomic sites
- Female Reproductive System [NCIt concept]
- Genitourinary System [NCIt concept]
- Reproductive System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Gestational choriocarcinoma [ORDO Disease]
- Gestational choriocarcinoma (disorder) [SNOMED CT concept]
- Gestational choriocarcinoma (morphologic abnormality) [SNOMED CT concept]
- gestational choriocarcinoma [DO Concept]
- gestational choriocarcinoma [Disease (Nov.)]
- molar pregnancy with choriocarcinoma [SNOMED Notion]
Validated automatic mappings to NTBT
- choriocarcinoma [Disease (Nov.)]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixture of Germ Cell Neoplastic Components Present [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Cytotrophoblastic Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Intermediate Type Trophoblastic Cell [NCIt concept]
- Malignant Syncytiotrophoblastic Giant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Trophoblastic Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Human Chorionic Gonadotropin-Positive Neoplastic Cells Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Pregnancy Complication [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Female Reproductive System [NCIt concept]
- Genitourinary System [NCIt concept]

Keyword's position in hierarchy(ies) :

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