Echinomycin - CISMeF

Preferred Label : Echinomycin;

NCIt synonyms : N,N'-(2,4,12,15,17,25-hexamethyl-11,24-bis(1-methylethyl)-27-(methylthio)-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa-28-thia-2,5,12,15,18,25-hexaazabicyclo(12.12.3)nonacosane-7,20-diyl)bis(2-quinoxalinecarboxamide); Quinomycin A; Echinomycin A; Bis-Quinoline Analogue; Levomycin;

NCIt definition : A polypeptide quinoxaline antineoplastic antibiotic isolated from the bacterium Streptomyces echinatus. Echinomycin intercalates into DNA at two locations simultaneously in a sequence-specific fashion, thereby inhibiting DNA replication and RNA synthesis. (NCI04);

UNII : TG824J6RQT;

CAS number : 512-64-1;

Molecule name : SK 302B; BRN 0078671;

NSC code : 526417;

Details

Origin ID

C462;

UMLS CUI

C0013508;

Automatic exact mappings (from CISMeF team)
- quinomycin [MeSH concept]
- quinomycin [MeSH Supplementary Concept]
- quinomycins [MeSH concept]
Currated CISMeF NLP mapping
- echinomycin [MeSH Descriptor]
- echinomycin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Antibiotic [UMLS semantic type]
UMLS correspondences (same concept)
- echinomycin [MeSH concept]
- echinomycin [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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