Thyroid Gland Hyperfunctioning Adenoma

Preferred Label : Thyroid Gland Hyperfunctioning Adenoma;

NCIt synonyms : Thyroid Gland Toxic Hyperfunctioning Adenoma; Thyroid Gland Toxic (Hyperfunctioning) Adenoma; Thyroid Gland Toxic Adenoma; Thyroid Gland Hot Adenoma;

NCIt definition : A thyroid gland adenoma producing thyroxin. It is associated with hyperthyroidism. Radioactive iodine scan reveals a hot nodule.;

Neoplastic status : Benign;

Details

Origin ID

C46122;

UMLS CUI

C1710419;

Automatic exact mappings (from CISMeF team)
- toxic nodular goiter, nos [SNOMED Notion]
Disease excludes abnormal cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease excludes normal cell origin
- Endocrine-Stromal Cell [NCIt concept]
Disease may have findings
- Radiation Toxicity [NCIt concept]
Has associated anatomic sites
- Endocrine Gland [NCIt concept]
- Endocrine System [NCIt concept]
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_cytogenetic_abnormality
- Loss of Chromosome 11q [NCIt concept]
- Loss of Chromosome 13q [NCIt concept]
- Loss of Chromosome 14q [NCIt concept]
- Loss of Chromosome 16q [NCIt concept]
- Loss of Chromosome 9p [NCIt concept]
- Loss of Chromosome 9q [NCIt concept]
disease_excludes_finding
- Borderline Lesion [NCIt concept]
- Capsular Invasion [NCIt concept]
- Ground Glass Nuclear Inclusion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Nuclear Clearing [NCIt concept]
- Nuclear Grooves [NCIt concept]
- Nuclear Pseudoinclusion [NCIt concept]
- Tumor Vascular Invasion [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Thyroid Gland Follicular Cell [NCIt concept]
disease_has_associated_disease
- Hyperthyroidism [NCIt concept]
disease_has_finding
- Benign Cellular Infiltrate [NCIt concept]
- Encapsulated Mass [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Follicular Structures Present [NCIt concept]
- Hot Nodule [NCIt concept]
- Monoclonal Cellular Population Present [NCIt concept]
- Nodular Lesion [NCIt concept]
- Thyroglobulin-Positive Neoplastic Cells Present [NCIt concept]
disease_has_normal_cell_origin
- Endocrine Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- Thyroid Gland Follicular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Follicle [NCIt concept]
- Thyroid Gland Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Endocrine Gland [NCIt concept]
- Endocrine System [NCIt concept]
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_mapped_to_gene
- PAX8/PPARG Fusion Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12 [NCIt concept]
- Gain of Chromosome 5 [NCIt concept]
- Loss of Chromosome 10 [NCIt concept]
- Loss of Chromosome 13 [NCIt concept]
- Loss of Chromosome 19 [NCIt concept]
- Loss of Chromosome 3p [NCIt concept]
- Trisomy 7 [NCIt concept]
disease_may_have_molecular_abnormality
- HRAS Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- NRAS Gene Mutation [NCIt concept]

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