Hereditary Thyroid Gland Medullary Carcinoma

Preferred Label : Hereditary Thyroid Gland Medullary Carcinoma;

NCIt synonyms : Familial Thyroid Gland Medullary Carcinoma;

NCIt related terms : familial medullary thyroid cancer; Hereditary Thyroid Gland Medullary Cancer;

NCIt definition : A medullary thyroid gland carcinoma inherited through an autosomal dominant mode. It is associated with multiple endocrine neoplasia type II (2a) or III (2b).;

Alternative definition : NCI-GLOSS: An inherited form of medullary thyroid cancer (cancer that forms in the cells of the thyroid that make the hormone calcitonin).;

Neoplastic status : Malignant;

Codes from synonyms : CDR0000563950;

Details

Origin ID

C46099;

UMLS CUI

C1833921;

Currated CISMeF NLP mapping
- Familial medullary thyroid cancer [MedDRA Preferred Term]
- Familial medullary thyroid carcinoma [ORDO Disease]
- Thyroid carcinoma, familial medullary [OMIM Phenotype]
- familial medullary thyroid carcinoma [Disease (Nov.)]
- familial medullary thyroid carcinoma [MeSH concept]
- familial medullary thyroid carcinoma [DO Concept]
- familial medullary thyroid carcinoma [MeSH Supplementary Concept]
Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease may have findings
- Cold Nodule [NCIt concept]
- Metastatic Malignant Neoplasm in the Lymph Nodes [NCIt concept]
- Organoid Pattern [NCIt concept]
- Trabecular Pattern [NCIt concept]
Excludes anatomical site(s)
- Lung [NCIt concept]
- Pituitary Gland [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Familial medullary thyroid cancer [MedDRA Preferred Term]
- Familial medullary thyroid carcinoma [ORDO Disease]
- Thyroid carcinoma, familial medullary [OMIM Phenotype]
- familial medullary thyroid carcinoma [MeSH Supplementary Concept]
- familial medullary thyroid carcinoma [MeSH concept]
- familial medullary thyroid carcinoma [DO Concept]
- familial medullary thyroid carcinoma [Disease (Nov.)]
Validated automatic mappings to NTBT
- Medullary thyroid cancer [MedDRA Preferred Term]
- Medullary thyroid carcinoma [HPO term]
- Medullary thyroid carcinoma [ORDO Disease]
- Medullary thyroid carcinoma (disorder) [SNOMED CT concept]
- thyroid cancer, medullary [MeSH concept]
- thyroid cancer, medullary [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_associated_disease
- Neoplastic C-Cell Hyperplasia [NCIt concept]
disease_has_associated_disease
- Multiple Endocrine Neoplasia Type 2 [NCIt concept]
- Multiple Endocrine Neoplasia Type 2A [NCIt concept]
- Multiple Endocrine Neoplasia Type 2B [NCIt concept]
disease_has_finding
- Calcitonin Positive Neoplastic Cells Present [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Hereditary Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Serum Calcitonin Level Increased [NCIt concept]
- Well-Circumscribed Lesion [NCIt concept]
disease_has_molecular_abnormality
- Activating RET Gene Mutation [NCIt concept]
- RET Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- C-Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Epithelial Tissue [NCIt concept]
- Thyroid Gland Follicle [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_mapped_to_gene
- RET Gene [NCIt concept]
disease_may_have_abnormal_cell
- Malignant Neuroendocrine Polygonal Cell [NCIt concept]
- Malignant Neuroendocrine Small Round Cell [NCIt concept]
- Malignant Neuroendocrine Spindle Cell [NCIt concept]
disease_may_have_associated_disease
- Multiple Endocrine Neoplasia Type 2A [NCIt concept]
- Multiple Endocrine Neoplasia Type 2B [NCIt concept]
- Paraneoplastic Syndrome [NCIt concept]
related_to_genetic_biomarker
- NTRK1 Gene [NCIt concept]
- RET Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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