Macrofollicular Variant Thyroid Gland Papillary Carcinoma

Preferred Label : Macrofollicular Variant Thyroid Gland Papillary Carcinoma;

NCIt definition : A morphologic variant of papillary carcinoma of the thyroid gland characterized by the predominance or the exclusive presence of macrofollicles. Some of the malignant follicular cells display the nuclear features that characterize the papillary adenocarcinomas of the thyroid gland.;

Neoplastic status : Malignant;

Details

Origin ID

C46092;

UMLS CUI

C1708851;

Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Cold Nodule [NCIt concept]
- Cystic Change [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Psammoma Body Formation [NCIt concept]
Excludes anatomical site(s)
- Extrahepatic Bile Duct [NCIt concept]
- Intrahepatic Bile Duct [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- High Grade Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Mucoid Stroma Formation [NCIt concept]
- Pseudopapillary Pattern [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Thyroid Gland Follicular Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Follicular Cell Differentiation [NCIt concept]
- Ground Glass Nuclear Inclusion [NCIt concept]
- Macrofollicular Structures Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Nuclear Clearing [NCIt concept]
- Nuclear Grooves [NCIt concept]
- Nuclear Pseudoinclusion [NCIt concept]
- Papillary Growth Pattern [NCIt concept]
- Thyroglobulin-Positive Neoplastic Cells Present [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Thyroid Gland Follicular Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Epithelial Tissue [NCIt concept]
- Thyroid Gland Follicle [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_mapped_to_gene
- CCDC6/RET Fusion Gene [NCIt concept]
- ERC1/RET Fusion Gene [NCIt concept]
- GOLGA5/RET Fusion Gene [NCIt concept]
- NCOA4/RET Fusion Gene [NCIt concept]
- PCM1/RET Fusion Gene [NCIt concept]
- PRKAR1A/RET Fusion Gene [NCIt concept]
- TPM3/NTRK1 Fusion Gene [NCIt concept]
- TRIM24/RET Fusion Gene [NCIt concept]
- TRIM33/RET Fusion Gene [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF NP_004324.2:p.V600E [NCIt concept]
- HRAS Gene Mutation [NCIt concept]
- KRAS Gene Mutation [NCIt concept]
- NRAS Gene Mutation [NCIt concept]
- NTRK1 Gene Rearrangement [NCIt concept]
- RET/PTC Rearrangement [NCIt concept]

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