NCIt definition : A study in which the participants are assigned by chance to separate groups to evaluate
treatments. The study also includes a control group, which is undergoing the same
rigors of the study with placebo treatment or standard treatment. The trial can also
be controlled by the addition of a test group to ensure there are no factors present
to skew the results and by the inclusion of peer-review analysis by appropriate government
officials. 2005;
Alternative definition : CDISC-GLOSS: A well-controlled clinical trial in which subjects are assigned to treatment
or control groups according to randomization principles. See randomization. [After
FDA and Clinical Drug Trials : A Short History, S.White Junod, 2008; CONSORT statement]
See also randomization, clinical trial, controlled study, adequate and well-controlled
studies.; MRCT-Ctr: Research that uses chance for participants to be assigned to the study treatment
group or a comparison group. (https://mrctcenter.org/glossaryterm/randomized-controlled-trial/); CDISC: A study design in which interventions are assigned to subjects according to
randomization principles.;