Sparsely Granulated Lactotroph Pituitary Neuroendocrine Tumor

Preferred Label : Sparsely Granulated Lactotroph Pituitary Neuroendocrine Tumor;

NCIt synonyms : Sparsely Granulated Pituitary Gland Lactotroph Adenoma; Sparsely Granulated Lactotroph PitNET/Adenoma; Sparsely Granulated Lactotroph Pituitary Neuroendocrine Tumor/Adenoma;

NCIt definition : A prolactin-producing pituitary neuroendocrine tumor composed of relatively large, chromophobic or slightly acidophilic cells with well developed, abundant endoplasmic reticulum, and many immature secretory granules. Mature secretory granules are sparse.;

Neoplastic status : Undetermined;

Details

Origin ID

C45932;

UMLS CUI

C1710139;

Automatic exact mappings (from CISMeF team)
- Prolactinoma [ORDO Disease]
Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Neoplastic Endothelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease excludes normal cell origin
- Endothelial Cell [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Base of the Skull [NCIt concept]
- Central Nervous System [NCIt concept]
- Head and Neck [NCIt concept]
- Nervous System [NCIt concept]
- Pituitary Gland [NCIt concept]
- Sellar Region [NCIt concept]
- Skull [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Giant Mitochondria Present [NCIt concept]
- Growth Hormone and Prolactin-Producing Neoplastic Cells Present [NCIt concept]
- Metastatic Lesion [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Adenohypophysial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Neoplastic Lactotroph Cell [NCIt concept]
- Neoplastic Lactotroph Cell with Small Secretory Granules [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Expression of Neuroendocrine Markers Present [NCIt concept]
- Misplaced Exocytosis Present [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Well Developed Rough Endoplasmic Reticulum Present [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_normal_cell_origin
- Adenohypophysial Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- Lactotroph Cell [NCIt concept]
- PIT1-Lineage Adenohypophysial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Anterior Lobe of the Pituitary Gland [NCIt concept]
disease_mapped_to_gene
- POU1F1 Gene [NCIt concept]

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