Mixed Somatotroph and Lactotroph Pituitary Neuroendocrine Tumor

Preferred Label : Mixed Somatotroph and Lactotroph Pituitary Neuroendocrine Tumor;

NCIt synonyms : Mixed GH-PRL Cell Adenoma; Mixed Somatotroph-Lactotroph Adenoma; Mixed Somatotroph-Lactotroph Pituitary Gland Adenoma; Mixed Somatotroph and Lactotroph PitNET/Adenoma; Mixed Somatotroph and Lactotroph Pituitary Neuroendocrine Tumor/Adenoma; Mixed Somatotroph and Lactotroph Adenoma;

NCIt related terms : Mixed Somatolactotrope Adenoma;

Alternative definition : NICHD: A pituitary neuroendocrine tumor composed of an admixture of acidophilic and chromophobic cells that produce growth hormone and prolactin, respectively. Unlike mammosomatotroph pituitary neuroendocrine tumors, these two hormones are not localized in the same cell by immunohistochemistry.;

Neoplastic status : Undetermined;

Details

Origin ID

C45927;

UMLS CUI

C1709052;

Automatic exact mappings (from CISMeF team)
- Somatomammotropinoma [ORDO Disease]
Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Base of the Skull [NCIt concept]
- Central Nervous System [NCIt concept]
- Head and Neck [NCIt concept]
- Nervous System [NCIt concept]
- Pituitary Gland [NCIt concept]
- Sellar Region [NCIt concept]
- Skull [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- NCIt Neoplasm Core Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Endocrinology Terminology [NCIt concept]
disease_excludes_finding
- Giant Mitochondria Present [NCIt concept]
- Metastatic Lesion [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Adenohypophysial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Lactotroph Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
- Neoplastic Somatotroph Cell [NCIt concept]
disease_has_finding
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Growth Hormone and Prolactin-Producing Neoplastic Cells Present [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_normal_cell_origin
- Acidophilic Cell [NCIt concept]
- Adenohypophysial Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- PIT1-Lineage Adenohypophysial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Anterior Lobe of the Pituitary Gland [NCIt concept]
disease_mapped_to_gene
- POU1F1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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