Densely Granulated Somatotroph Pituitary Neuroendocrine Tumor

Preferred Label : Densely Granulated Somatotroph Pituitary Neuroendocrine Tumor;

NCIt synonyms : Densely Granulated Pituitary Gland Somatotroph Adenoma; Densely Granulated Somatotroph Pituitary Neuroendocrine Tumor/Adenoma; Densely Granulated Somatotroph PitNET/Adenoma;

NCIt definition : A growth hormone-producing pituitary neuroendocrine tumor composed of medium-sized acidophilic cells with granular cytoplasm and abundant secretory granules.;

Neoplastic status : Undetermined;

Details

Origin ID

C45925;

UMLS CUI

C1707675;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Lactotroph Cell [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Base of the Skull [NCIt concept]
- Central Nervous System [NCIt concept]
- Head and Neck [NCIt concept]
- Nervous System [NCIt concept]
- Pituitary Gland [NCIt concept]
- Sellar Region [NCIt concept]
- Skull [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Growth Hormone and Prolactin-Producing Neoplastic Cells Present [NCIt concept]
- Metastatic Lesion [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Adenohypophysial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
- Neoplastic Somatotroph Cell [NCIt concept]
- Neoplastic Somatotroph Cell with Abundant Secretory Granules [NCIt concept]
disease_has_finding
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Well Developed Rough Endoplasmic Reticulum Present [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_normal_cell_origin
- Adenohypophysial Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
- PIT1-Lineage Adenohypophysial Cell [NCIt concept]
- Somatotroph Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Glandular Epithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Anterior Lobe of the Pituitary Gland [NCIt concept]
disease_mapped_to_gene
- GNAS Gene [NCIt concept]
- POU1F1 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 17 [NCIt concept]
- Gain of Chromosome 19 [NCIt concept]
- Gain of Chromosome 22 [NCIt concept]
- Gain of Chromosome 5 [NCIt concept]
- Gain of Chromosome 9 [NCIt concept]
- Loss of Chromosome 1 [NCIt concept]
- Loss of Chromosome 11 [NCIt concept]
- Loss of Chromosome 18 [NCIt concept]
- Loss of Chromosome 2 [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Inactivation [NCIt concept]
- GNAS Gene Mutation [NCIt concept]

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