Mediastinal Germ Cell Tumor with Somatic-Type Malignancy

Preferred Label : Mediastinal Germ Cell Tumor with Somatic-Type Malignancy;

NCIt definition : A rare extragonadal germ cell tumor that arises from the mediastinum and is associated with the presence of a somatic-type malignant component. The somatic malignancy is usually a sarcoma (e.g., embryonal rhabdomyosarcoma, angiosarcoma, or leiomyosarcoma), adenocarcinoma, squamous cell carcinoma, adenosquamous carcinoma, or primitive neuroectodermal tumor. The prognosis is poor.;

Neoplastic status : Malignant;

Details

Origin ID

C45732;

UMLS CUI

C1708954;

Disease excludes abnormal cell
- Neoplastic Sex Cord-Stromal Cell [NCIt concept]
Disease may have findings
- Chest Pain [NCIt concept]
- Cough [NCIt concept]
- Hoarseness [NCIt concept]
- Respiratory Distress [NCIt concept]
- Superior Vena Cava Syndrome [NCIt concept]
Excludes anatomical site(s)
- Gonad [NCIt concept]
- Neck [NCIt concept]
Has associated anatomic sites
- Mediastinum [NCIt concept]
- Respiratory System [NCIt concept]
- Thoracic Cavity [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Germ Cell [NCIt concept]
disease_has_associated_disease
- Somatic-Type Malignancy [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Sarcomatous or Carcinomatous Component Present [NCIt concept]
disease_has_normal_cell_origin
- Germ Cell [NCIt concept]
disease_has_normal_tissue_origin
- Germinal Layer [NCIt concept]
disease_has_primary_anatomic_site
- Mediastinum [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Gain of Chromosome 12p [NCIt concept]
- i(12p) [NCIt concept]

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