" /> HTR2A 1 Allele - CISMeF





Preferred Label : HTR2A 1 Allele;

NCIt synonyms : HTR2A-C; HTR2A-C Allele; HTR2A A2; 5-Hydroxytryptamine (Serotonin) Receptor 2A A2 Allele; HTR2A, 102T C; HTR2A A2 Allele; HTR2A: g102T C; HTR2A C;

NCIt definition : HTR2A-C Allele is a variant form of 20-kb 3-exon human HTR2A Gene (GPCR1/5HT2 Family), which encodes Serotonin 5-HT-2A Receptor, a conserved integral membrane 5-HT/serotonin receptor protein involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production by association with G proteins that activate a PI-calcium second messenger system. 5-HT is a biogenic hormone that affects specific receptors as a neurotransmitter, hormone, or mitogen. HTR2A contains several polymorphic sites. Different alleles differ in the concentration of RNA and protein product of 5HTR2A. HTR2A-C Allele contains a single-nucleotide polymorphism (102 T C) in an intron and is expressed at a lower level than the 102 C T allele.;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
29/04/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.