Preferred Label : ABCB1 1 Allele;
Obsolete resource : true;
NCIt synonyms : MDR1-C; MDR1-C Allele; ABCB1-C Allele; P-Glycoprotein Transporter C Allele; ABCB1-C;
NCIt definition : Human ABCB1-C allele is the wild-type form of the human ATP-binding cassette, sub-family
B (MDR/TAP), member 1 (ABCB1) gene (ABC gene family), located at located at 7q21.1,
which encodes multidrug resistance protein 1. Amplification of the ABCB1 gene is a
major determinant in the development of multi-drug resistance which decreases the
effectiveness of many chemotherapeutic agents used in cancer treatment.;
NCIt note : See 'ABCB1 wt Allele';
Concept status : Retired_Concept;
Origin ID : C45683;
OMIM relation
- Semantic type(s)
