Preferred Label : Chronic Eosinophilic Leukemia, Not Otherwise Specified;
NCIt synonyms : Eosinophilic Leukemia; CEL; CEL, NOS;
NCIt related terms : Chronic eosinophilic leukemia, NOS; Chronic eosinophilic leukemia/hypereosinophilic syndrome; chronic eosinophilic leukemia; CEL/Hypereosinophilic syndrome;
NCIt definition : A rare myeloproliferative neoplasm characterized by a clonal proliferation of eosinophilic
precursors resulting in persistently increased numbers of eosinophils in the blood,
marrow and peripheral tissues. Since acute eosinophilic leukemia is at best exceedingly
rare, the term eosinophilic leukemia is normally used as a synonym for chronic eosinophilic
leukemia. In cases in which it is impossible to prove clonality and there is no increase
in blast cells, the diagnosis of idiopathic hypereosinophilic syndrome is preferred.
(WHO, 2001);
Alternative definition : NCI-GLOSS: A disease in which too many eosinophils (a type of white blood cell) are
found in the bone marrow, blood, and other tissues. Chronic eosinophilic leukemia
may stay the same for many years, or it may progress quickly to acute leukemia.;
Neoplastic status : Malignant;
ICD-O code : 9964/3;
Codes from synonyms : CDR0000426408; 10065872;
Origin ID : C4563;
UMLS CUI : C0346421;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- DO Cross reference
- Disease may have findings
- False automatic mappings
- Has associated anatomic sites
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to NTBT
- concept_is_in_subset
- disease_excludes_finding
- disease_excludes_molecular_abnormality
- disease_has_abnormal_cell
- disease_has_finding
- disease_has_normal_cell_origin
- disease_has_normal_tissue_origin
- disease_has_primary_anatomic_site
- disease_may_have_associated_disease
- disease_may_have_cytogenetic_abnormality
- disease_may_have_normal_cell_origin
