Pulmonary Lymphomatoid Granulomatosis

Preferred Label : Pulmonary Lymphomatoid Granulomatosis;

NCIt synonyms : Lung Lymphomatoid Granulomatosis;

NCIt definition : A rare lymphoproliferative disorder that affects the lungs. It is characterized by the presence of an angiocentric and angiodestructive polymorphic cellular infiltrate composed of EBV-positive neoplastic B-lymphocytes and reactive T-lymphocytes. The majority of patients present with bilateral nodular lesions in the lungs. The prognosis depends on the histologic grade of the lesions. One third of patients with grade 1 lesions and two thirds of patients with grade 2 lesions progress to non-Hodgkin lymphoma. Grade 3 lesions, by definition, are classified as non-Hodgkin lymphomas.;

Neoplastic status : Uncertain Malignant Potential;

Details

Origin ID

C45607;

UMLS CUI

C1260886;

CISMeF manual mappings
- Lymphomatoid granulomatosis of lung (disorder) [SNOMED CT concept]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Fever [NCIt concept]
- Malaise [NCIt concept]
- Musculoskeletal Pain [NCIt concept]
- Weight Loss [NCIt concept]
Excludes anatomical site(s)
- Neck [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
- Lung [NCIt concept]
- Lymphatic System [NCIt concept]
- Respiratory System [NCIt concept]
- Thoracic Cavity [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Lymphomatoid granulomatosis of lung (disorder) [SNOMED CT concept]
disease_has_abnormal_cell
- Abnormal Hematopoietic and Lymphoid Cell [NCIt concept]
- Abnormal Lymphocyte [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_associated_disease
- EBV Infection [NCIt concept]
disease_has_finding
- Angiocentric Pattern [NCIt concept]
- Angiodestructive Pattern [NCIt concept]
- Borderline Lesion [NCIt concept]
- Chronic Inflammatory Infiltrate [NCIt concept]
- Epstein-Barr Virus Positive [NCIt concept]
- Premalignant Lesion [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- EBV-Transformed Mature B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
- Mature Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lung [NCIt concept]
- Lymphatic System [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients